Synthetic vaccine nanoparticles target to lymph node triggering enhanced innate and adaptive antitumor immunity
… synthetic vaccine nanoparticles (SVNPs) that efficiently targeted lymph nodes, where immune
… antigens are primed, were developed to enhance antitumor immunity. The size (20–70 nm…
… antigens are primed, were developed to enhance antitumor immunity. The size (20–70 nm…
Synthetic nanovaccines for immunotherapy
… Here, we discuss the development of nanoparticle vaccine (… lymph node targeting, antigen
presentation, and stimulation of … that boost anti-tumor immunity to synergize with immune …
presentation, and stimulation of … that boost anti-tumor immunity to synergize with immune …
Engineering strategies for lymph node targeted immune activation
Y Chen, S De Koker, BG De Geest - Accounts of chemical …, 2020 - ACS Publications
… nanoparticle delivery to lymph nodes: (1) direct lymph node … surface will enhance B cell
activation by triggering multiple B … PhD in Immunology on the development of synthetic vaccine …
activation by triggering multiple B … PhD in Immunology on the development of synthetic vaccine …
Nanotechnology-based approaches to promote lymph node targeted delivery of cancer vaccines
R He, J Zang, Y Zhao, H Dong, Y Li - ACS Biomaterials Science & …, 2022 - ACS Publications
… inhibits and eliminates cancer by activating the immune system. … vaccines to reactivate
antitumor immune response and … or chemical synthesis, achieve the specific targeting with locally …
antitumor immune response and … or chemical synthesis, achieve the specific targeting with locally …
Synthetic nanoparticles for vaccines and immunotherapy
… defense against pathogens and antitumor immunity and “M2” … a productive activating immune
response. Importantly, once … Nanoparticle targeting of adjuvants to lymph nodes can thus …
response. Importantly, once … Nanoparticle targeting of adjuvants to lymph nodes can thus …
Nanoparticles for immune stimulation against infection, cancer, and autoimmunity
… ) potentiates existing antitumor immune responses and induces … When tumor-draining lymph
nodes (TDLN) were targeted by … in draining lymph nodes and triggered strong CD8+ T-cell …
nodes (TDLN) were targeted by … in draining lymph nodes and triggered strong CD8+ T-cell …
Nanoparticle drug delivery systems designed to improve cancer vaccines and immunotherapy
… by targeting nanovaccines to tumor-draining lymph nodes … microbubbles to allow
ultrasound-triggered transfection of DCs. … designed to elicit anti-tumoral immune responses. In …
ultrasound-triggered transfection of DCs. … designed to elicit anti-tumoral immune responses. In …
Engineered nanoparticles for cancer vaccination and immunotherapy
… of tumor antigens as immune targets while exploiting … to lymph nodes, generating strong
antitumor T cell immunity. … able to elicit antitumor immunity against disseminated tumors…
antitumor T cell immunity. … able to elicit antitumor immunity against disseminated tumors…
Targeting the innate immune system with nanoparticles for cancer immunotherapy
K Li, Z Zhang, Y Mei, M Li, Q Yang, Q Wu… - Journal of Materials …, 2022 - pubs.rsc.org
… microenvironment to enhance antitumor immunity. Such … ) in lymph nodes, the tumor immune
microenvironment and … triggering potent macrophage-related anti-tumor immune responses…
microenvironment and … triggering potent macrophage-related anti-tumor immune responses…
[HTML][HTML] Targeting the tumor-draining lymph node with adjuvanted nanoparticles reshapes the anti-tumor immune response
… aims to activate or enhance the patient's adaptive immune system to kill tumor … Treatment
with immune cell-activating adjuvant without co-… Nanoparticle synthesis and characterization …
with immune cell-activating adjuvant without co-… Nanoparticle synthesis and characterization …